Oral, colon-specific drug delivery has attracted much interest recently. It is of considerable advantage to have an oral drug delivery system that could be targeted to the colon. This could be either for the local treatment ...

Spheronization is a rapid process for production of microspheres. The process involves the dry mixing ofdrug with microcrystalline cellulose (MCC), which on subsequent wetting with water forms a plasticmass suitable for ...

In attempt to improve the biological activity of the well-known drug hydroxychloroquine (HQC), eight derivatives (HQ1-4Py – HQ8-4Py) based on the core of HQC were design and their electronic properties including frontier ...

Background:- Dicarbonyl compounds such as methylglyoxal and glyoxal have been identified as the predominant source for the formation of advanced glycation end products (AGE) in various tissues contributing to aging and ...

Extrusion – spheronization technology is one of the major methods for production of multiparticulates in the pharmaceutical industry. The difficulty in this method is how to develop a formulation ...