El‑Mahdi, Idris; A El-Shehebia, Tariq(Lebda Medical Journal, 2016-04-18)
Extrusion – spheronization technology is one of the major methods for production of multiparticulates in the pharmaceutical industry. The difficulty in this method is how to develop a formulation ...
A El-Shhibia, Salma; M.El-Mahdi, Idris(Department of Pharmaceutics, Faculty of Pharmacy, University of Benghazi, 2017-07-26)
Spheronization is a rapid process for production of microspheres. The process involves the dry mixing ofdrug with microcrystalline cellulose (MCC), which on subsequent wetting with water forms a plasticmass suitable for ...
M El-Mahdi, Idris; A El-Shhibia, Salma(Lebda Medical Journal, 2017-10-02)
Oral, colon-specific drug delivery has attracted much interest recently. It is of considerable
advantage to have an oral drug delivery system that could be targeted to the colon. This
could be either for the local treatment ...
Alnajjar, Radwan; Kawafi, Nagwa; Elmhdw, Maraia; Kamunya, Stephanie; Eltumi, Salem; F. Mohamed, Najwa(Department of Pharmaceutical chemistry, Benghazi University, Libya, 2020-12-02)
In this work, Atorvastatin, one of the most selling drugs in the world for cardiovascular
disease, was studied theoretically. Density functional theory (DFT) calculations were
carried out on the four optical enantiomers ...
Al-Qirim, prof.Tariq; Al-Qerem, Dr. Waleed; Sari, prof.youssef; Bryant-Friedrich, Dr. Amanda; Hikmat, Dr. Suhair; Harb, Dr. Mohammad; Mohamed, Dr. Negia; Abul-Futooh, Dr. Hassan; Ali Al-Qirim, MSc. Rania; Abu Sheikha, Prof. Ghassan; Al-Essa, Dr. Luay; Hamed, Dr. Rania; Al-Hiari, Prof. Yusuf; Al Bawab, Dr. Abdel Qader; Hamadneh, Dr. Lama; Alhusban, Dr. Ala`(Al-Zaytoonah University of Jordan and The University of Toledo Seventh International Pharmaceutical Conference (ZTIPC 2019), 2019-11-07)
Alnajjar, Radwan; Mohamed, Najwa; Kawafi, Nagwa(Department of Chemistry, Faculty of Science, University of Benghazi, Libya, 2020-11-09)
Hyperlipidemia influences on numerous diseases, such as atherosclerosis, hypertension, and diabetes mellitus,
however it still treatable. Atorvastatin is one of the most common statins; yet, it has poor solubility due to ...
El Mehdi, Eman; Sahoo, Rashmirekha; A Ahmed, Musa; Mohamed rghigh, Abir; Al Geilania, Abdelsalam; Sahoo, Soumendra(Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al -Arab Medical Science University, Benghazi, Libya, 2008-06-02)
Non-enzymic glycation of long-lived proteins has been implicated in several age related and diabetes related complications,
including cataract. Dicarbonyl compounds such as methylglyoxal and glyoxal have been identified ...
A. Algeryani, Safa; F. Al Shwihdy, Najwa; Omar, Ruwida; El-shinitri, Nouha; A. Alnajjar, Radwan(Department of Medicinal Chemistry, Faculty of Pharmacy, 2020-09-24)
Annona muricata also known as a Grviola is a fruit tree with a long history of traditional use. A. muricata has a wide array
of ethnomedicinal activities and containing wide range of chemical compounds including Alkaloids ...
Starting from the concept of "similar molecules exert similar biological activities" to modify structures of biologically
active molecules or readily available drugs to improve their therapeutic activity or reduce side ...
Sahoo, Soumendra; Sahoo, Rashmirekha; El Mehendi, Iman; Abuajila Ahmad, Musa(JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL SCIENCES, 2012-09-23)
Background:- Dicarbonyl compounds such as methylglyoxal and glyoxal have been identified as the predominant source
for the formation of advanced glycation end products (AGE) in various tissues contributing to aging and ...
M.K. Omar, Ruwida; M. Najar, Adel; Bobtaina, Eman; F. Elsheikh, Awad(Department of Pharmaceutical chemistry, Benghazi University, Libya, 2020-08-16)
In attempt to improve the biological activity of the well-known drug hydroxychloroquine (HQC), eight derivatives (HQ1-4Py – HQ8-4Py) based
on the core of HQC were design and their electronic properties including frontier ...