Effect of Salvadora persica (Miswak) extracts against bacteria isolated from mouth compared with other pathogenic bacteria and antibiotics

Abstract

Salvadora persica , commonly known as miswak (tooth brush), belongs to the family Salvadoracea It is widely distributed in the arid regions of India and often on saline soils. It is an upright evergreen small tree or shrub, The fresh leaves are eaten as salad and are used in traditional medicine for cough, asthma, scurvy, rheumatism, piles, and other diseases. The use of miswak is a pre-Islamic custom, which was adhered to by the ancient Arabs to get their teeth white and shiny. Studied the effect of the extracts of Salvadora Percica (alcohol and water) against eight types of bacteria isolated from the mouth men and women Staphylococcus aureus, Streptococcus mutans, Streptococcus faecalis ,Streptococcus pyogenis, Enterococcus faecalis and Staphylococcus mutans . And other types obtained from the laboratory of microbiology at the Benghazi Medical Center and Children's Hospital medical as follows Escherichia coli , Pseudomonas aeruginosa ,klebsiella pnemoniae algala , Staphylococcus albus ,Streptococcus pnemoniae, Acinetobacter baumannii urine, proteus mirabilis algala and Staphylococcus epidrimidis urine. Micococcus lylae, Bacillus stearothermophilus, by using disk diffusion method in the dishes. The extracts of water and alcohol have never been inhibited against all isolates at concentrations of 30%, 50% and 100%, with the exception of the water extract of boiled water that did not inhibit the growth of all bacteria. The alcohol extract recorded the highest inhibitory zone of the water extract, 25.33 mm at 100% concentration while inhibition zone 21:33 mm at 100% less concentration than alcohol extract. The lowest inhibitory zone was 12 mm diameter and the lowest inhibitory zone was 9.67 mm diameter and was the best effect For extracts on bacteria at 100% concentration for both water extracts And alcohol. whenever a high concentration effect whenever the better. The study also showed that the effect of both extracts of cold and alcoholic aqueous plants was higher than the effect of antibiotics. Therefore, this study showed that it is possible to use abstractions As a low-cost drug substitute and free from side effects instead of biogas with side effects.