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Gestational diabetes effect on the histological structure of human Placenta

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dc.contributor.author Ali, Halima A
dc.contributor.author Sati, Ali I
dc.contributor.author Mansur, Hoda S
dc.contributor.author Muftah, Saleh S
dc.contributor.author Amghaiab, Iman E
dc.date.accessioned 2020-10-06T13:00:02Z
dc.date.available 2020-10-06T13:00:02Z
dc.date.issued 2019-12-28
dc.identifier.issn 2663-1407
dc.identifier.uri http://repository.uob.edu.ly/handle/123456789/1301
dc.description.abstract Many studies have been carried on the placenta of diabetic mothers to determine the changes in placenta structure as an adaptation to the diabetic environment. These changes are one of the detrimental fetal outcomes regardless of the good care of diabetic women. The aim of this study is to recognize the histological changes in the placenta of pregnant women with gestational diabetes and the effect of these changes on fetal and neonatal mortality and morbidity. The study was done on 30 placentae from diagnosed pregnant women with gestational diabetes treated with insulin. The control group involves 30 placentae obtained from normal healthy women. Both groups of placentae were full-term and post caesarean delivery. The biopsies of the placentae were collected from the central and peripheral regions and treated to obtain paraffin sections, and then stained with Masson’s Trichrome stain. Under a light microscope, the sections were examined and photographed by using a digital camera. An increase in chorionic villi vasculature and a number of young villi were observed in the placentae of diabetic group. These changes could clarify the increase of morbidity and mortality in fetal and neonate associated with diabetes. On the other hand, these histological changes could be modifying changes as it has been shown that functions of the placenta were not severely distressed, as a result, of diabetes, as there are compensative adjusting responses. en_US
dc.language.iso en en_US
dc.publisher Universty of Benghazi en_US
dc.relation.ispartofseries Volume 10, Number 1;1
dc.subject Human placentae en_US
dc.subject Gestational diabetes en_US
dc.subject Chorionic villi en_US
dc.subject Histological changes. en_US
dc.title Gestational diabetes effect on the histological structure of human Placenta en_US
dc.type Working Paper en_US

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