Synthesis and Evaluation of Biological Activity of Pyrazolone Compounds

Hind, Abd Alati Alzletni

dc.contributor.author	Hind, Abd Alati Alzletni
dc.date.accessioned	2024-07-26T18:31:21Z
dc.date.available	2024-07-26T18:31:21Z
dc.date.issued	2021-01
dc.identifier.uri	https://repository.uob.edu.ly/handle/123456789/1965
dc.description.abstract	Treatment of a mixture of 3-methyl-1-phenylpyrazol-5-one 1 with a diversity of aromatic aldehydes and piperidine in absolute ethanol (24 h at 0 ºC) gave products in good yields. Biological screening of the synthesized derivatives for their antimicrobial activity against various bacteria (gram positive and gram negative) as well as against fungi have been evaluated, where derivatives 3 and 11 were found to be the most potent. Characterization of all the formed derivatives was emphasized by melting point determination, NMR data in addition to their mass spectra.	en_US
dc.language.iso	en	en_US
dc.publisher	جامعة بنغازي	en_US
dc.subject	pyrazolone	en_US
dc.subject	Benz aldehydes	en_US
dc.subject	Pathological microorganisms	en_US
dc.title	Synthesis and Evaluation of Biological Activity of Pyrazolone Compounds	en_US
dc.type	Working Paper	en_US