ACTA SCIENTIFIC MICROBIOLOGY Antimicrobial Activity and Antioxidant Studies of (Z)-2-(2-Methoxybenzylideneamino)- 3-Methylbutanoic Acid with Mixed Ligand Chelates

Abstract

The present study summarizes the antimicrobial and antioxidant activities of the synthesized Schiff base; (z)-2-(2- methoxybenzylideneamino)-3-methylbutanoic acid (L1) and its Co(II) and Ni(II) complexes. The Schiff base and its chelates were tested for their antimicrobial activities, it is found that the tested compounds are active against microorganisms used (staphylococcus aureus, Streptococcus pyogenes, Bacillus, Klebsiellapneumonia, Pseudomonas aeruginosa, Escheriehia coli, Aspergillus niger, Penicillium chrysogenum) when compared with the activity of the reference or standard drugs (Gentamici and Ampicillin). on the other hand, the antioxidant activity was measured with a simple and rapid free radical assay using DPPH. Where he was the higher antioxidant activity of Ni(II) relative to the other synthesized complex.